As a result of the widespread application of urinary catheterization, catheter-associated urinary tract infection (CAUTI) is the most common healthcare associated infection. To fasten recovery and reduce the risk of a recurrent CAUTI, current guidelines recommend to replace the catheter at the onset of a CAUTI when the indwelling catheter has been in place for more than 2 weeks. This recommendation, however, is based on limited evidence. Additionally, there is significant practice variation in the Netherlands regarding catheter replacement in CAUTI.
Given the limited evidence and significant practice variation in the Netherlands, this randomized trial is needed. We hypothesize that not changing the urinary catheter during a CAUTI is non-inferior to changing the catheter on the risk of a recurrent CAUTI. The aim of this study is to provide an evidence-based recommendation for urinary catheter management during CAUTI treatment.